Scientific Research

Health claims for our products are supported by peer-reviewed scientific publications

EFSA Approved Claims
PubMed Publications
Registered Food Supplement

About the Scientific Research

All health claims for the ingredients in our products are based on scientific research published in peer-reviewed scientific journals and are available in the PubMed database of the US National Institutes of Health (NIH). The claims are approved by the European Food Safety Authority (EFSA) under Regulation (EC) No 1924/2006.

Vitamin D

EFSA Approved
Vitamin D and the Immune System
Aranow C Journal of Investigative Medicine. 2011;59(6):881-886
PubMed: 21527855
Results: Vitamin D receptors are expressed in immune cells. Vitamin D modulates innate and adaptive immune responses. Deficiency is associated with increased susceptibility to infections.
Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality
Holick MF Autoimmunity Reviews. 2013;12(10):976-989
PubMed: 23542507
Results: A comprehensive review of the evidence for the role of Vitamin D in musculoskeletal health, immune function, and bone density.
Vitamin D and muscle function
Ceglia L Current Opinion in Clinical Nutrition and Metabolic Care. 2009;12(6):628-633
PubMed: 19770647
Results: Vitamin D receptors are found in skeletal muscle. Vitamin D deficiency is linked to muscle weakness.

Vitamin E

EFSA Approved
Vitamin E in human health and disease
Rizvi S, Raza ST, Ahmed F, et al. Sultan Qaboos University Medical Journal. 2014;14(2):e157-165
PubMed: 24790736
Results: Vitamin E is a potent antioxidant that protects cell membranes from oxidative damage.
The Role of Vitamin E in Human Health and Some Diseases
Traber MG, Atkinson J Free Radical Biology and Medicine. 2007;43(1):4-15
PubMed: 17561088
Results: Vitamin E (alpha-tocopherol) is the primary fat-soluble antioxidant in the human body.

Vitamin C

EFSA Approved
Vitamin C and Immune Function
Carr AC, Maggini S Nutrients. 2017;9(11):1211
PubMed: 29099763
Results: Vitamin C supports various cellular functions of both the innate and adaptive immune systems.
Vitamin C in Disease Prevention and Cure: An Overview
Chambial S, Dwivedi S, et al. Indian Journal of Clinical Biochemistry. 2013;28(4):314-328
PubMed: 24426232
Results: An overview of the antioxidant properties of Vitamin C and its role in collagen synthesis and immune function.

Zinc

EFSA Approved
Zinc status and serum testosterone levels of healthy adults
Prasad AS, Mantzoros CS, Beck FW, et al. Nutrition. 1996;12(5):344-348
PubMed: 8875519
Results: Zinc deficiency is associated with decreased serum testosterone levels in healthy men. Zinc supplementation in deficient men leads to an increase in testosterone levels.
Effect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm count
Netter A, Hartoma R, Nahoul K Archives of Andrology. 1981;7(1):69-73
PubMed: 7271365
Results: Zinc sulfate administration increases sperm count and plasma testosterone levels in infertile men.
Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health
Fallah A, Mohammad-Hasani A, Colagar AH Journal of Reproduction & Infertility. 2018;19(2):69-81
PubMed: 30009140
Results: Zinc is critical for male fertility, affecting spermatogenesis, sperm quality, and testosterone synthesis.

Magnesium

EFSA Approved
Magnesium in Prevention and Therapy
Gröber U, Schmidt J, Kisters K Nutrients. 2015;7(9):8199-8226
PubMed: 26404370
Results: Magnesium is essential for ATP production and muscle function. Deficiency is linked to muscle cramps and fatigue.
The effect of magnesium supplementation on primary insomnia in elderly
Abbasi B, Kimiagar M, et al. Journal of Research in Medical Sciences. 2012;17(12):1161-1169
PubMed: 23853635
Results: Magnesium supplementation improves sleep quality and reduces fatigue.

Vitamin K2 (MK-7)

EFSA Approved
Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women
Knapen MH, Schurgers LJ, Vermeer C Osteoporosis International. 2007;18(7):963-972
PubMed: 17287908
Results: Vitamin K2 (MK-7) supplementation improves bone geometry and strength.
Three-year low-dose menaquinone-7 supplementation helps decrease bone loss
Knapen MH, Drummen NE, et al. Osteoporosis International. 2013;24(9):2499-2507
PubMed: 23525894
Results: MK-7 supplementation helps decrease bone loss by activating osteocalcin.

Vitamin B6

EFSA Approved
Vitamin B6 and Its Role in Cell Metabolism and Physiology
Parra M, Stahl S, Hellmann H Cells. 2018;7(7):84
PubMed: 30037155
Results: Vitamin B6 is a cofactor in over 140 enzymatic reactions, including steroid hormone metabolism.
Vitamin B6 and its role in steroid hormone action
Allgood VE, Cidlowski JA Endocrine Reviews. 1992;13(4):644-671
PubMed: 1332448
Results: Vitamin B6 modulates the action of steroid hormones, including androgens.

Vitamin B12

EFSA Approved
Vitamin B12 deficiency
Hunt A, Harrington D, Robinson S BMJ. 2014;349:g5226
PubMed: 25189324
Results: B12 deficiency leads to fatigue, weakness, and neurological issues.
Vitamin B12: An Essential Vitamin with Important Functions
O'Leary F, Samman S Nutrients. 2010;2(3):299-316
PubMed: 22254022
Results: Vitamin B12 is essential for DNA synthesis and energy production.

Vitamin B9 (Folate)

EFSA Approved
Folate and human reproduction
Ebisch IM, Thomas CM, et al. Human Reproduction Update. 2007;13(2):163-174
PubMed: 17099205
Results: Folate is critical for cell division and reproduction.
Folic acid and mechanisms of disease
Blom HJ, Smulders Y Proceedings of the Nutrition Society. 2011;70(3):295-302
PubMed: 21635791
Results: Folate participates in DNA synthesis and methylation reactions.

Selenium

EFSA Approved
Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men
Safarinejad MR, Safarinejad S Journal of Urology. 2009;181(2):741-751
PubMed: 19027106
Results: Selenium (200 μg/day) significantly improves sperm motility, morphology, and concentration.
The effect of oral selenium supplementation on human sperm motility
Scott R, MacPherson A, et al. British Journal of Urology. 1998;82(1):76-80
PubMed: 9643619
Results: Selenium improves sperm motility in subfertile men.
Selenium and Thyroid Disease: From Pathophysiology to Treatment
Ventura M, Melo M, Carrilho F International Journal of Endocrinology. 2017
PubMed: 28286502
Results: Selenium is essential for thyroid hormone metabolism.

Ashwagandha

Traditional Use
Note: Ashwagandha does not have EFSA-approved health claims. The listed studies are for informational purposes and demonstrate the traditional use of the herb in Ayurvedic medicine.
A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of ashwagandha root extract
Chandrasekhar K, Kapoor J, Anishetty S Indian Journal of Psychological Medicine. 2012;34(3):255-262
PubMed: 23439798
Results: A randomized study examining the traditional use of Ashwagandha for overall well-being.
Examining the effect of Withania somnifera supplementation on muscle strength and recovery
Wankhede S, Langade D, et al. Journal of the International Society of Sports Nutrition. 2015;12:43
PubMed: 26609282
Results: A study on the traditional use of Ashwagandha in men practicing strength training.
An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda
Singh N, Bhalla M, et al. African Journal of Traditional Medicine. 2011;8(5 Suppl):208-213
PubMed: 22754076
Results: An overview of the traditional use of Ashwagandha in Ayurveda as an adaptogenic herb.

Tribulus

Traditional Use
Note: Tribulus does not have EFSA-approved health claims. The listed studies are for informational purposes and demonstrate the traditional use of the herb in Eastern medicine.
Tribulus terrestris: chemical composition and pharmacological activities
Chhatre S, Nesari T, et al. Phytotherapy Research. 2014;28(8):1125-1136
PubMed: 24458633
Results: A review of the chemical composition of Tribulus and its traditional use in various cultures.
Tribulus terrestris for treatment of sexual dysfunction: randomized double-blind placebo-controlled study
de Souza KZ, Vale FB, et al. Daru. 2016;24(1):14
PubMed: 27316745
Results: A study examining the traditional use of Tribulus in folk medicine.

Important Disclaimer

The cited scientific studies are provided for informational purposes only and do not constitute medical advice. TG Labs products are food supplements and are not intended to diagnose, treat, cure, or prevent any disease.

Health claims for vitamins and minerals are approved by the European Food Safety Authority (EFSA) under Regulation (EC) No 1924/2006. There are no approved health claims for Ashwagandha and Tribulus.

Individual results may vary. If you have any underlying health conditions, consult a physician before use.

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